GPAT Practice Test Online
- Pharmacy Entrance Examination 2017 GPAT questions answers are applicable for any kind of GPAT Entrance preparation in India. You can practice as much as you can to gather knowledge of how to answers GPAT Entrance critical type papers in short time and this can be a big factor for cracking all India level exam.
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GPAT Practice Test Online
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Question 1 |
Quinoline alkaloids are biosynthesized via which one of the following pathways?
Shikimic acid - tyrosine | |
Shikimic acid - tryptophan | |
Shikimic acid -
cathinone | |
Shikimic acid - phenylalanine |
Question 2 |
Khellin is an active constituent of which one of the following plants?
Prunus serona | |
Tribulus terrestis | |
Ammi visnaga | |
Vanilla planifolia |
Question 3 |
Which one of the following compounds is useful for the stimulation of cell divisionand release of lateral bud dormancy?
Zeatin | |
2,4-Dichlorophenoxyacetic acid | |
Indoleacetic acid | |
Picloram |
Question 4 |
A powdered drug has the following microscopic characters:Anther cells, arenchyma, pollen grains, phloem fibers, volatile oil cells and stone cells. The powder is obtained from which of the followings?
Clove bud powder | |
Clove bud powder with stalk | |
Mother Clove | |
None of the above |
Question 5 |
Which of the following ergot alkaloids is water soluble and shows blue fluorescence?
Ergosine | |
Ergotamine | |
) Ergocristine | |
) Ergometrine |
Question 6 |
Goldbeater's skin test is used to detect the presence of which one of the following classes of compounds?
Tannins | |
Steroids | |
Glycerides | |
Resins |
Question 7 |
Phenylethylisoquinoline is the precursor of which of the following alkaloids?
Colchicine | |
Papaverine | |
Emetine | |
Cephaline |
Question 8 |
Arrange the following fatty acids in decreasing order of their unsaturation (highest to lowest):[P] Stearic [Q] Oleic acid [R] Linolenic acid [S] Linoleic acid
P>Q>R>S | |
S>R>P>Q | |
R>S>Q>P | |
Q>P>R>S |
Question 9 |
Each Of the following options lists a phytoconstituent, its phytochemical grouping, pharmacological activity and corresponding semisynthetic analogue. Find a MISMATCHING option.
Podophyllotoxin, lignan, anticancer, etoposide | |
Sennoside, anthraquinone, laxative, sinigrin | |
Atropine, alkaloid, anticholinergic, homatropine | |
THC. terpenophenolic, psychoactive, nabilone |
Question 10 |
Which of the following mechanisms is NOT related to platelet aggregation inhibitory action?
ADP receptor antagonism | |
Glycoprotein IIb/IIIa receptor antagonism | |
Phosphodiesterase inhibition | |
Prostacvclin inhibition |
Question 11 |
Which of the following species is being inactivated by the enzyme Dipeptidylpeptidase-4?
Oxytocin | |
Vasopressin | |
Incretin | |
Glucagon |
Question 12 |
Two genetic types of Cannabis i.e. drug type and Hemp type are cultivated.[P] Drug type cannabis is rich in (-)A-trans-tetrahydrocannabinol .[Q] Hemp type cannabis is rich in cannabidiol[R] Drug type cannabis is rich in cannabidiol -[S] Hemp type cannabis contains elongated bast fibresWhich one of the given statements is correct?
P is true, Q is true, R is true, S is true | |
P is true, Q is false, R is false, S is true | |
P is true, Q is true, R is false, S is true | |
P is false, Q is false, R is true, S is false |
Question 13 |
Inhibition/induction of which of the following Cytochrome P450enzyme system is most likely to be involved in important drug-druginteractions?
CYP3A4 | |
CYP2D6 | |
CYP2C9 | |
CYP1A2 |
Question 14 |
Choose the correct statement about the given four diseases?[P] Cardiomyopathy ],Q] Rheumatoid arthritis [R] Myasthenia gravis [S] Ulcerative colitis
Q & S are autoimmune disorders | |
P & Q are autoimmune disorders | |
P & R are not autoimmune disorders | |
R & S are not autoimmune disorders |
Question 15 |
Most of the emergency contraceptives have one of the following active ingredients?
Estradiol | |
Norethindron | |
Misoprostol | |
Levonorgesterel |
Question 16 |
Antiretroviral Raltegravir is unique, because of which of its following actions?
Integrase inhibition | |
CCR5 Co-receptor antagonism | |
Fusion inhibition | |
Reverse transcriptase inhibition |
Question 17 |
Which one of the followings is NOT an example of G-protein coupled receptor?
Muscarinic cholinergic receptor | |
Alpha adrenoceptor | |
Nicotinic cholinergic
receptor | |
Beta adrenoceptor |
Question 18 |
Which of the following statements is FALSE for artemisinin?
It is a sesquiterpene lactone endoperoxide | |
It is a drug of choice in prophylaxis of malaria | |
It does not cure relapsing malaria | |
It is useful in treatment of cerebral falciparum malaria |
Question 19 |
Which of the following antibiotics produces concentration dependent bactericidal action and also possesses post-antibiotic effect?
Ceftazidime | |
Azithromycin | |
Amikacin | |
Piperacillin |
Question 20 |
What is chemotaxis?
Toxicity of chemicals | |
Taxonomy of chemicals | |
Inhibition of Inflammation | |
Movement of leucocytes in inflammation |
Question 21 |
Which of the followings used in the treatment of rheumatoid arthritis is NOT a biologic response modifier?
Anakinra | |
Leflunomide | |
Etanercept | |
Infliximab |
Question 22 |
Which of the followings is a noncompetitive inhibitor of the enzyme reversetranscriptase in HIV?
Lamivudine | |
Nevirapine | |
Abacavir | |
Tenofovir |
Question 23 |
Which one of the followings is a beta lactamase inhibitor?
Penicillanic acid | |
Embonic acid | |
Cephalosporanic acid | |
Clavulanic acid |
Question 24 |
Neural tube defects may occur by which one of the following anti-seizure drugs?
Ethosuximide | |
Vigabatrin | |
Valproic acid | |
Primidone |
Question 25 |
Which one of the following drying methods is commonly used in pharma industry for drjing of soft shell capsules?
Truck drying | |
Fluid bed drying | |
Vacuum drying | |
Microwave drying |
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GPAT Question Answers Mock Test
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Question 1 |
If C is the concentration of dissolved drug and Cs is the saturation concentration. In which case the sink conditions are said to be maintained?
C < 20% of Cs | |
C > 20% of Cs | |
C < 10% of Cs | |
C >10% of Cs |
Question 2 |
All of the followings are indications for use of ACE inhibitors EXCEPT for one. Identify that.
Hypertension | |
Myocardial infarction | |
Left ventricular dysfunction | |
Pheochromocytoma |
Question 3 |
Which water is used for hand washing in a change room of pharmaceutical manufacturing plant?
Potable water | |
Purified water | |
Disinfectant water | |
Soap water |
Question 4 |
Which one of the followings does NOT afford a macromolecular inclusioncompound?
Zeolites | |
Dextrins | |
Silica gels | |
Cyclodextrins |
Question 5 |
Which condition does not apply as per Indian law while conducting single dose bioavailability study of an immediate release product?
Sampling period should be atleast three t1/2 ei | |
Sampling should represent pre-exposure, peak exposure and post-exposure phases | |
There should be atleast four sampling points during elimination phase | |
Sampling should be continued till measured AUC is atleast equal to 80% of AUC |
Question 6 |
Which of the following isothem are produced when the heat of condensation of successive layers is more than the heat of adsorption of first layer?
Type III and IV | |
Type II and V | |
Type I and III | |
Type III and V |
Question 7 |
The minimal effective flow rate of air in Luminar Flow hood should be not less than how many cubic feet per minute?
10 | |
50 | |
100 | |
1000 |
Question 8 |
Which of the following pumps is used in handling of corrosive liquids?
Turbine pump | |
Volute Pump | |
Air binding pump | |
Baltic pump |
Question 9 |
Convert 90% v/v alcohol to Proof strength. Choose the correct answer.
57.77° under proof | |
57.77° over proof | |
47.41° over proof | |
47.41° under proof |
Question 10 |
What is the Heat of vaporization of water at 100:
2790 cal/ mole | |
7290 cal / mole | |
7920 cal/mole | |
9720 cal/mole |
Question 11 |
Which of the followings act as a non-ionic emulsifying agent?
Triethanolamine oleate | |
Polyoxyethylene sorbitan monooleate | |
N-Cetyl-N-ethylmorpholinium ethosulfate | |
Dioctyl sulphosuccinate |
Question 12 |
Which of the following Schedules include shelf life of drugs?
Schedule F | |
Schedule M | |
Schedule G | |
Schedule P |
Question 13 |
By addition of which of the followings the shells of soft gelatin capsules may be made elastic?
Polyethylene glycol | |
Sorbitol | |
Propylene glycol | |
Dibutyl phthalate |
Question 14 |
Department of Transport Test (DOT) is performed for which of the followings?
Strip packing | |
Aerosols | |
Injection packing | |
Glass containers |
Question 15 |
How many mL of 50% (w/v) dextrose solution and how many mL of 5% (w/v)dextrose solution are required to prepare 4500 mL of a 10% (w/v) solution?
500 mL of 50% and 4000 mL of 5% | |
1000 mL of 50% and 3500 mL of 5% | |
4000 mL of 50% and 500 mL of 5% | |
1500 mL of 50% and 3000 mL of 5% |
Question 16 |
P-Glycoprotein pump is responsible for which one of the followings?
Transporting the drugs from the enterocytes into the gut lumen | |
Transporting the drugs from gut lumen into enterocytes | |
Transporting the drugs from oral mucosa into blood capillaries | |
Transporting the drugs from Peyer's patches into the gut lumen. |
Question 17 |
The first stage of wetting on addition of a granulating agent to the powders is characterized by which one of the followings?
Capillary state | |
Pendular state | |
Funicular state | |
Droplet state |
Question 18 |
The degree of flocculation of a suspension is 1.5 and the sedimentation volume is 0.75. What will be the ultimate volume of deflocculated suspension?
2.0 | |
1.5 | |
0.75 | |
0.5 |
Question 19 |
A drug is administered to a 65 Kg patient as 500 mg tablets every 4 hours. Half- life of the drug is 3 h, volume of distribution is 2 liter/Kg and oral bioavailability of the drug is 0.85. Calculate the steady state concentration of the drug?
5.05mcg/ml | |
4.50 mcg/ml | |
3.53 mcg/ml | |
3.00 mcg/ml |
Question 20 |
Statement [X] : Hofmeister series grades coagulating power of electrolytes as per their ionic size. Statement [Y] : The relative coagulating power is given by:[P] Al+++ > Ba++ [Q] Li- > F- [R] NH4+ > Na+ Choose the correct statement :
Statement X is true but P, Q and R are false in Statement Y | |
Statement X is false and P, Q and R are false in Statement Y | |
Statement X is true and Q and R are false in Statement Y | |
Statement X is false and P is false in Statement Y |
Question 21 |
Larger values of Ky in the Heckel Plot indicate formation of what quality of tablets?
Harder tablets | |
Softer tablets | |
Fluffy tablets | |
Brittle tablets |
Question 22 |
Which is NOT applicable to protein binding?
Klotz reciprocal plot | |
Sandberg modified equation | |
Blanchard equation | |
Detli plot |
Question 23 |
According to USP, the speed regulating device of the dissolution apparatus should be capable of maintaining the speed within limits of what % of the selected speed?
1% | |
2% | |
4% | |
5% |
Question 24 |
Which statement is NOT true for steam distillation?
It is also called differential distillation | |
It can be used for separation of immiscible liquids - | |
It can be applied for volatile substances | |
It can be used for separation of miscible liquids |
Question 25 |
What is Primogel?
Substituted HPMC for direct compression | |
Modified microcrystalline cellulose for direct compression | |
Hydro gelling polymer for gel formation | |
Modified starch for disintegration |
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