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Pharmaceutical Chemistry Quiz Question & Answers

Pharmaceutical Chemistry Quiz Question & Answers (Question Bank) Free Online Test For Medical Students like PG, PHD, Specialist exam entrance.

We have put total 50 Objective Type Question Answers on Pharmaceutical Chemistry, you can practice these question answers for free. Well you can also check list of Online Medical Entrance Mock Test / Quiz question comes from different areas on Medical.

Pharmaceutical Chemistry Quiz Question & Answers

This Pharmaceutical Chemistry Quiz questions answers are applicable for any kind of Medical PG Entrance exam or job related exam especially for PHD, MD, MS, M.Ch., D.M, Medical Students. You can practice as much as you can to gather knowledge of how to answers Pharmaceutical Chemistry Quizeach question having four alternate answers, once you select one answers of Pharmaceutical Chemistry Quiz, system will show you whether its correct or not.



Pharmaceutical Chemistry Quiz Question & Answers (Total 50 MCQs)

Pharmaceutical Chemistry Online Mock Test (high Level)

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Question 1
Chemical nomenclature of procaine is
A
2-Diethylaminoethyl-4-aminobenzoate
B
4-Aminobenzamidoethyl amine
C
N,N-Diethyl 4- aminobenzoate
D
4-Amino-2-diethylaminoethyl benzoate
Question 2
Mestranol is
A
3-Methyl ether of ethinyl estradiol
B
3-Cyclopentyl ether of ethinyl estradiol
C
17-Methyl ether of ethinyl estradiol
D
17-Cyclopentyl ether of ethinyl estradiol
Question 3
1,2-Diketones in presence of base yields -hydroxy carboxylic acid. This is which type of re-arrangement
A
Claisen condensation
B
Benzillic acid rearrangement
C
Perkin's reaction
D
Wittig reaction
Question 4
Clavulanic acid is beta-lactam ring fused with
A
Thienyl system
B
Oxazolidine system
C
Thiadiazole system
D
Thiazolidine system
Question 5
The rate limiting step in the biosynthesis of catecholamines is
A
Decarboxylation of dihydroxyphenylalanine
B
Hydroxylation of phenylalanine
C
Hydroxylation of tyrosine
D
Oxidation of dopamine
Question 6
λmax of benzalaldehyde is 250 nm. What is λmax of p-hydroxy benzaldehyde? 
A
253 nm
B
261 nm
C
275 nm
D
270 nm
Question 7
Sulfa drugs are assayed by which type of titration?
A
Acid-base titration
B
Redox titration
C
Diazotization titration
D
Non aqueous titration
Question 8
IUPAC name of Prazosin is
A
1-(4-amino-6,7-dimethoxy-2-quinazolyl)-4-(2-furoyl)piperidine
B
1-(4-amido-6,7-dimethoxy-2-quinazolyl)-4-(2-furoyl)piperidine
C
1-(4-amino-6,7-dimethyl-2-quinazolyl)-4-(2-furoyl)piperidine
D
1-(4-amino-6,7-dimethoxy-2-quinazolyl)-4-(2-furoyl)piperazine
Question 9
Qualitative analysis in polarography is based upon
A
Electrode potential
B
Migration current
C
Half wave potential
D
Limiting current
Question 10
Electrophilic aromatic substitution reactions in indole gives
A
2-Subtituted indole
B
5-Subtituted indole
C
6-Subtituted indole
D
3-Subtituted indole
Question 11
Indomethacin is synthesized from 
A
p-anisidine
B
γ picoline
C
o-anisidine
D
α-picoline
Question 12
Starting material for the synthesis of Amitryptyline is
A
Phthalic anhydride
B
Phthalamic acid
C
Terephthalic acid
D
Phthalimide
Question 13
Acidity of ascorbic acid is due to presence of
A
Free Craboxylic acid
B
Hydroxyl groups
C
Enolic groups
D
Amide group
Question 14
In the design of captopril, the
A
-COOH group is introduced in proline to enhance the binding capability at the receptor site
B
-SH group is introduced to enhance the binding to the zinc ion of ACE
C
-SH group is introduced to enhance the binding capability of the drug with cobalt ion of ACE
D
-COOH and -SH groups are used to introduce hydrophilic pockets at the receptor site
Question 15
Which of the following compound produces H2 gas when added to the water? 
A
LiH
B
CH4
C
NH3
D
H2S
Question 16
Acyclovir is synthesized by alkylation reaction between 1-benzoyloxy-2chloromethoxyethane in triethylamine with
A
Adenine
B
Cytosine
C
Guanine
D
Uracil
Question 17
In thiazides following substituent is essential for diuretic activity
A
Chloro group at position 6
B
Sulphamoyl group at position 7
C
Methyl group at position 2
D
Hydrophobic group at position 3
Question 18
In Hoffmann rearrangement reaction
A
Acids are converted to amines
B
Acids are converted to alcohol
C
Amines are converted to amides
D
Primary amides are converted to amines
Question 19
A widely accepted detector electrode for pH measurement is
A
Platinum electrode
B
Silver chloride electrode
C
Glass electrode
D
Mercury mercurous chloride electrode
Question 20
Oxidation of galactose with conc. HNO3 yields
A
Mucic acid
B
Glucuronic acid
C
Saccharic acid
D
Gluconic acid
Question 21
The epimers of glucose is
A
Fructose
B
Galactose
C
Ribose
D
Deoxyribose
Question 22
Prostaglandins are synthesized in the body from
A
Myristic acid
B
Stearic acid
C
Arachidonic acid
D
Lignoceric acid
Question 23
Synthesis of urea takes place excessively in
A
Kidney
B
Gall bladder
C
Urinary bladder
D
Liver
Question 24
In cannizaro reaction, two moles of aldehydes reacts to give
A
Amines and ketones
B
Ketones and acids
C
Acids and alcohol
D
Ketones and alcohol
Question 25
Drug which inhibit absorption of cholesterol in the body
A
Lovastatin
B
Ezetimibe
C
Simvastatin
D
Nicotinic acid
Question 26
Cardiac glycosides have the following configuration in the aglycone part of steroidal nucleus
A
5α , 14β
B
5β , 14α
C
5β , 14β
D
5α , 14α
Question 27
Karl Fischer reagent does not contain one of the following constituent
A
Ethanol
B
Pyridine
C
Iodine
D
Sulfur dioxide
Question 28
Number of carbon atoms in Cholesterol is
A
27
B
26
C
25
D
23
Question 29
Carbonic anhydrase is competitively inhibited by
A
Allopurinol
B
Acetazolamide
C
Aminopterin
D
Neostigmine
Question 30
Chemical shift in NMR spectroscopy is expressed by
A
cm-1
B
Ampere
C
Parts per million
D
mm/ml
Question 31
Choose the correct statement regarding the synthesis of phenyl n-propyl ether
A
It can be prepared from bromobenzene and sodium n-propoxide.
B
It can be prepared from chlorobenzene and phenol
C
It can be prepared from benzyldehyde and sodium n-propoxide
D
It can be prepared from n-propyl bromide and sodium phenoxide
Question 32
The reaction of nitrogen dioxide with water yields
A
Only HNO3
B
Only HNO2
C
HNO3 and NO
D
HNO3 and NO2
Question 33
What is the oxidation state of chromium in the (NH4)2Cr2O2
A
+7
B
+6
C
+5
D
+4
Question 34
For -OH group stretching bands in IR spectra will be obtained at
A
900-675 cm-1
B
3700-3500 cm-1
C
1750-1725 cm-1
D
2260-2210 cm-1
Question 35
4-Hydroxy-3-hydroxy methyl benzaldehyde is treated with acetic anhydride and the kept with solvent ether, t-butyl cyanide and acetic acid for ten days. Resulting product is reduced with LiAlH4 in tetrahydrofuran. The final product is 
A
Isoprenaline
B
Salbutamol
C
Dobutamine
D
Orciprenaline
Question 36
Assay of Sulphamethoxazole is done by
A
UV-Visible spectroscopy
B
Nitrite titration
C
Potentiometric method
D
High Performance Liquid Chromatography
Question 37
In the synthesis of chiral drug molecule, in symmetric environment
A
Always one enantiomer obtained
B
Always both enantiomers obtained in unequal amount
C
Always both enantiomers obtained in equal amount
D
Always one enantiomer and one diastereomer obtained
Question 38
Nitrogen is 
A
Sp hybridized
B
Sp3 hybridized
C
Sp2 hybridized
D
Sp3 d hybridized
Question 39
Hyperconjugation is also known as
A
No bond resonance
B
Polarization
C
Field effect
D
Inductive effect
Question 40
The peak with highest mass to charge ratio in mass spectra is
A
Molecular ion peak
B
Base peak
C
Metastable ion peak
D
Fragment ion peak
Question 41
Chemical structure of digitoxigenin is different from gitoxigenin due to 
A
Presence of -COOH group at 16th position
B
Absence of -OH group at 16th position
C
Presence of methyl group at 16th position
D
Absence of methyl group at 16th position
Question 42
Clonidine hydrochloride anα 2-agonist contains which type of ring system in its structure
A
Imidazoline
B
Quinoline
C
Pyrazole
D
Indole
Question 43
SN1 reactions undergo rearrangement because in their intermediate step reaction forms
A
Carbenes
B
Carbanions
C
Nitrenes
D
Carbocation
Question 44
Official method for assay of Ciprofloxacin is
A
Gas Chromatography
B
High Performance Liquid Chromatography
C
Potentiometry
D
Non aqueous titration
Question 45
Which primary standard is used for standardization of NaOH solution?
A
Zinc metal
B
Potassium hydrogen phthalate
C
Potassium iodate
D
Sodium carbonate
Question 46
Ion which is used for calibration of flame photometer is
A
Lithium
B
Sodium
C
Calcium
D
Potassium
Question 47
In NMR, the magnetic field is varied continuously by
A
Sweep generator
B
Magnet
C
Radio frequency transmitter
D
Radio frequency receiver
Question 48
Antihypertensive drug with a tetrazole ring is
A
Clonidine
B
Captopril
C
Valsartan
D
Carbapenams
Question 49
H2-receptors are blocked by
A
Diphenhydramine
B
Mepayramine
C
Pyrilamine
D
Cimetidine
Question 50
In which type of titration pure metal are used as primary standard?
A
Acid base titration
B
Oxidation- reduction titration
C
Precipitation titration
D
Complex formation titration
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