Biochemistry Quiz Question & Answers

Biochemistry Quiz Question & Answers (Question Bank) Free Online Test For Medical Students like PG, PHD, Specialist exam entrance.

We have put total 50 Objective Type Question Answers on Biochemistry, you can practice these question answers for free. Well you can also check list of Online Medical Entrance Mock Test / Quiz question comes from different areas on Medical.

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Biochemistry Quiz Question & Answers (Total 50 MCQs)

Biochemistry Online Mock Test - High Level

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Question 1
Tay-Sachs disease, an inherited human disease resulting from abnormal accumulation of membrane lipids is caused due to the deficiency of:
A
Hexosaminidase A
B
Alpha-galactosidase A
C
Glucocerbrosidase
D
Sphingomyelinase
Question 2
Before addition of a poly A tail the primary transcript is cleaved by the endonuclease at a point 10 to 30 nucleotides downstream to the sequence
A
AAUAAA
B
UAAAUA
C
UUAUUU
D
AUAUAA
Question 3
Coenzyme A is a derivative of:
A
Pantothenic acid
B
Riboflavin
C
Pyridoxine
D
Thiamine
Question 4
All of the following are tumor suppressor genes ECXEPT:
A
p53
B
Rb1
C
Src
D
PTEN
Question 5
All of the following are the distinctive features of cancer cells EXCEPT:
A
Dedifferentiation
B
Anchorage independent growth
C
Contact inhibition
D
High mitotic rate
Question 6
Glycolysis is regulated by all of the following enzymes EXCEPT :
A
Hexokinase
B
Phosphofructokinase
C
Aldolase
D
Pyruvate kinase
Question 7
The 2014 Nobel Prize in Physiology or Medicine has been awarded to John O' Keefe, May-Britt Moser and Edward I. Moser for their discoveries:
A
Of cells that constitute a positioning system in the brain
B
Of machinery regulating transport of vesicle traffic, a major transport system in our cells
C
That mature cells can be reprogrammed to become pluripotent
D
Concerning the activation if innate immunity
Question 8
All of the following are true for both T and B lymphocytes EXCEPT that they:
A
Differentiate into memory cells
B
Mature to plasma cells
C
Are normally not sensitized by self antigens
D
Undergo the process of positive and negative selection
Question 9
Complement is activated by all of the following EXCEPT:
A
Mannen binding lectins
B
Bacterial endotoxins
C
Antigen-antibody complex
D
Monomeric IgG
Question 10
For excretion the drug isoniazid, used in the treatment of tuberculosis is subjected to:
A
Conjugation with glutathione
B
Sulphation
C
Methylation
D
Acetylation
Question 11
Acetyl CoA Carboxylase, the most important enzyme in the regulation lipogenesis is inhibited by all of the following EXCET by:
A
Glucagon
B
Epinephrine
C
Acyl-CoA
D
Citrate
Question 12
A purine analog used for treatment of Herpes virus infection that requires metabolism to its phosphorylated compound to yield active drug is:
A
Hydroxyurea
B
Tiazofurin adenine dinucleotide
C
Acyclovir
D
3'azido-3'deoxythymidine
Question 13
The phase of cell cycle characterized by synthesis of new protein is:
A
S
B
G2
C
M
D
G0
Question 14
All of the following are glycerol phospholipids EXCEPT:
A
Phosphatidic acid
B
Phosphatidyl choline
C
Cardiolipin
D
Ceremide
Question 15
The vitamin involved in oxidation reduction reactions whose deficiency causes Cheliosis and Angular somatitis is:
A
Thiamine
B
Riboflavin
C
Niacin
D
Folic acid
Question 16
All of the following are involved in generation of antibody diversity EXCEPT:
A
Availability of multiple V gene segments
B
Combinatorial diversity
C
Somatic hypermutations
D
mRNA trans-splicing
Question 17
The choice of the correct amino acid for the covalent attachment to its tRNA is made by:
A
Aminoacyl tRNA synthetase
B
Acceptor arm of tRNA
C
Anticodon arm of tRNA
D
Amino acid itself
Question 18
In E. Coli the primary enzyme of DNA replication is:   
A
DNA polymerase I
B
DNA polymerase II
C
DNA polymerase II
D
DNA polymerase IV
Question 19
Of the following RNA enzyme is:  
A
RNA polymerase
B
Reverse transcriptase
C
Klenow fragment
D
Peptidyl transferase
Question 20
All of the following neurological disorders are caused due to expansion of the repeating triplet CAG EXCEPT:
A
Fragile X syndrome
B
Mytonic dystrophy
C
Huntington's disease
D
Kennedy's disease
Question 21
The 21st amino acid specified by a t-RNA is:
A
γ-carboxyglutamate
B
Ornithine
C
Selenocysteine
D
Homocysteine
Question 22
The end product of β -oxidation in peroxisomes is:
A
Hexanoyl CoA
B
Octanoyl CoA
C
Propionyl Co A
D
Acetyl Co A
Question 23
Histones least tightly bound to chromatin are:
A
H1
B
H2A
C
H3
D
H4
Question 24
Triple stranded DNA is a feature of:  
A
A-DNA
B
B-DNA
C
H-DNA
D
Z-DNA
Question 25
The second messenger for all the following hormones is cAMP EXCEPT for:
A
hCG
B
FSH
C
PTH
D
Insulin
Question 26
Deficiency of lysosomal 1-4 and 1-6 glucosidase results in:
A
von Gierke's disease
B
Pompe's disease
C
Here's disease
D
Tarui's disease
Question 27
The mitochondria of brown fat contain a unique protein thermogenin in their inner membranes which:
A
Uncouples oxidative Phosphorylation
B
Facilitate electron transfer
C
Shuttles NADH
D
Shuttles FADH
Question 28
The net gain of ATP molecules in complete oxidation of palmitic acid is:
A
131
B
129
C
127
D
125
Question 29
The two purine nucleotides found in RNA: 
A
Are formed from a common intermediate in a branched pathway
B
Are formed in a sequencial pathway
C
Must come exogenous source
D
Are formed by oxidation of their deoxy forms
Question 30
Pyruvate dehydrogenase complex requires all of the following coenzymes or prosthetic groups EXCEPT:
A
Coenzyme A
B
NAD
C
Biotin
D
Lipoate
Question 31
The only step in TCA cycle in which substrate level phosphorylation takes place is catalyzed by :
A
Isocitrate dehydrogenase
B
Succinyl CoA synthase
C
Fumerase
D
Malate dehydrogenase
Question 32
Hyperhomocysteinemia, a risk factor for cardiovascular diseases and often found in elderly population is due to the inadequate intake/utilization of all of the following EXCEPT:
A
Folate
B
Vitamin B2
C
Vitamin B6
D
Vitamin B12
Question 33
All of the following are ketone bodies EXCEPT:
A
Acetone
B
Acetoacetate
C
α-ketoglutarate
D
β-hydroxy butyrate
Question 34
Zellweger's syndrome, a rare inherited disorder characterized by accumulation of C26-C38polyenoic acids in brain tissue is caused due to theabsence of:
A
Lysosomes
B
Peroxisomes
C
Microsomes
D
Endosomes
Question 35
Carnitine Palmitoyl Transferase II which catalyzes the conversion of Acyl CoA into Acyl carnitine is located in the:
A
Cytosol
B
Outer mitochondrial membrane
C
Inner mitochondrial membrane
D
Mitochondrial matrix
Question 36
All of the following amino acids have aromatic R groups EXCEPT:
A
Phenylalanine
B
Histidine
C
Tyrosine
D
Tryptophan
Question 37
Of the following the only amino acid which cannot be converted into oxaloacetate in animal tissues and hence not glucogenic is:
A
Lysine
B
Glycine
C
Serine
D
Aspartate
Question 38
Linkage disequilibrium means two different genes are:
A
Located on different chromosomes
B
Do not influence each others inheritance
C
Tend to be co-inherited
D
Adversely affect each other's inheritance
Question 39
Cyanide totally arrests respiration by inhibiting:
A
Respiratory chain between cytochrome b and c
B
Cytochrome oxidase
C
Transfer of reducing equivalents from succinate dehydrogenase to Q
D
NADH linked dehydrogeanases
Question 40
Uric acid is:
A
Formed from xanthine in the presence of oxygen
B
A degradation product of cytidine
C
Deficient in gout
D
A competitive inhibitor of xanthine oxidase
Question 41
Excess dietary Zinc inhibits the absorption of:
A
Calcium
B
Iron
C
Copper
D
Selenium
Question 42
An amino acyl tRNA analog that causes premature polypeptide chain termination is:
A
Erythromycin
B
Puromycin
C
Streptomycin
D
Tetracycline
Question 43
DNA mismatch repair is carried out in the vicinity of hemi-methylated sequence:
A
GATC
B
CATG
C
ATGC
D
TAGC
Question 44
The transcriptionally active locus of a eukaryotic genome is identified by its hypersensitivity to:
A
DNase I
B
RNase H
C
Mung bean Nuclease
D
Proteinase K
Question 45
Long term use of corticosteroid leads to the deficiency of all of the following EXCEPT:
A
Vitamin D
B
Vitamin K
C
Calcium
D
Zinc
Question 46
In all animal tissues the substrate for glycogen synthesis is:
A
UDP-Glucose
B
ADP-Glucose
C
GDP-Mannose
D
GDP-Glucose
Question 47
The peptide bond is rigid because it is a:
A
Single bond
B
Partial double bond
C
Double bond
D
Triple bond
Question 48
The monosaccharide whose intravenous injection can delete liver's store of Pi and activates glycolysis and lactate production is:
A
Glucose
B
Galactose
C
Mannose
D
Fructose
Question 49
The only eukaryotic transcription factor that has the ability to unwind DNA at the promoter region, phosphorylate Pol II and recruit nucleotide excision repair proteins is:
A
TFII A
B
TFII B
C
TFII F
D
TFII H
Question 50
Philadelphia chromosome occurring in chronic myeloid leukemia results due to reciprocal translocation between chromosomes:
A
8 and 14
B
8 and 22
C
9 and 14
D
9 and 22
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